Important Safety Information|Prescribing Information
Do not take SPRIX®:
  • if you’ve had asthma, hives, or other allergic-type reactions to aspirin, ketorolac, other NSAIDs, or EDTA
  • to prevent pain before any major surgery
  • during labor and delivery
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Bottle of SPRIX®

SPRIX® Savings Coupon

PAY NO MORE THAN $25* FOR A PRESCRIPTION OF SPRIX®
(ketorolac tromethamine) NASAL SPRAY

How patients can save

  • Insured Patients: Savings will apply only after initial $25 out-of-pocket expense is met. Maximum benefit is $100 per fill.
  • Cash Patients: Patient pays initial out-of-pocket of $5 per bottle. Maximum benefit $5 per bottle up to $25 per fill.
  • Maximum benefit from multiple transactions not to exceed $250 per patient per year.


For complete Prescribing Information including Boxed Warning and Medication Guide, please click here

Number of Savings Coupons to Print

(minimum of 1, maximum of 10)



 

*Offer Details: Offer is only valid for savings off patient’s SPRIX® (ketorolac tromethamine) Nasal Spray prescription. Each offer is only valid for a single prescription of 5 bottles or less. Maximum benefit from multiple transactions not to exceed $250 per patient per year. Offer may not be combined with any other program offer or discount. If patient has any questions regarding eligibility or benefits or if patient wishes to discontinue participation, they may call 1-877-264-2440 (8:00 am-8:00 pm EST, Monday-Friday). Patient is not eligible if a prescription is paid in full or part by any state or federally funded programs, including, but not limited to Medicare or Medicaid, Medigap, VA or DOD or TriCare, or where prohibited by law. When patient uses the SPRIX® Savings Card, he /she is certifying they are 18 years of age or older and understands the program rules, regulations, and terms and conditions and agree to comply with the terms above.





What Is the Most Important Information I Should Know About SPRIX®?
  • Do not use SPRIX® alone or before or after other forms of ketorolac for more than 5 days in a row. SPRIX® should be used exactly as prescribed, at the lowest dose possible, and for the shortest time needed. Always follow your doctor’s instructions about how often to use SPRIX®. If you still have pain after 5 days, please contact your doctor or healthcare provider. SPRIX® should not be used if you are under 18 years or for minor or long-term painful conditions.

  • Gastrointestinal Risk: SPRIX® can cause serious ulcers and bleeding in the stomach or intestines at any time during treatment, which can happen without warning symptoms and may cause death. Do not use SPRIX® if you have or have a history of peptic ulcer disease or stomach or intestinal bleeding or perforation. The chance of getting an ulcer or bleeding increases with taking medicines called corticosteroids and anticoagulants, longer use, smoking, drinking alcohol, patients 65 and over, and having poor health.

  • Bleeding Risk: SPRIX® reduces the ability of blood to clot and should not be used if you have or may have bleeding in the brain, a tendency to bleed, a decreased ability for blood to clot, or a high risk of bleeding.

  • Cardiovascular Risk: SPRIX® may increase the chance of a heart attack or stroke that can lead to death. This chance increases if you take NSAIDs for longer periods or if you have heart disease. SPRIX® should never be used right before or after a heart surgery called a “coronary artery bypass graft” (CABG) or before any major surgery.

  • Kidney Risk: SPRIX® should not be used if you have significantly reduced kidney function or if you are at risk for kidney failure due to low fluid levels (volume depletion). SPRIX® may cause kidney problems in patients taking angiotensin-converting-enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARBs).
Do not take SPRIX® (ketorolac tromethamine) Nasal Spray:
  • if you’ve had asthma, hives, or other allergic-type reactions to aspirin, ketorolac, other NSAIDs, or EDTA

  • to prevent pain before any major surgery

  • during labor and delivery

  • at the same time as injectable or oral ketorolac, aspirin, or other NSAIDs, or with probenecid or pentoxifylline

Tell your healthcare provider:
  • about all of your medical conditions and all of the medicines you take. SPRIX® and some other medicines can interact with each other and cause serious side effects. SPRIX® may reduce the effectiveness of blood pressure medications such as ACE inhibitors/ARBs and certain diuretics (water pills)

  • if you are pregnant. Use of NSAID medicines (at or after 30 weeks of pregnancy) can harm your baby

  • if you are breastfeeding. Some SPRIX® (ketorolac tromethamine) Nasal Spray may pass into your breast milk and can harm your baby

Serious side effects of SPRIX® may include: heart attack, stroke, high blood pressure, heart failure from body swelling (fluid retention), kidney problems including kidney failure, bleeding and ulcers in the stomach and intestine, low red blood cells (anemia), life-threatening skin reactions, life-threatening allergic reactions, liver problems including liver failure, and asthma attacks in people who have asthma.


Get emergency help right away if you have the following symptoms: shortness of breath or trouble breathing, chest pain, weakness in one part or side of your body, slurred speech, or swelling of the face or throat.

Stop SPRIX® and call your healthcare provider right away if you have any of the following symptoms:
nausea, more tired or weaker than usual, itching, your skin or eyes look yellow, stomach pain, flu-like symptoms, vomiting blood, there is blood in your bowel movement or it is black and sticky like tar, unusual weight gain, skin rash or blisters with fever, or swelling of the arms, legs, hands or feet.

SPRIX® can reduce the ability of the body to show signs of infection (fever and inflammation).

Keep SPRIX® away from your eyes. If you get SPRIX® in your eyes, wash out the eye with water or saline, and call a doctor if irritation persists for more than an hour.


The most common side effects of SPRIX® are: discomfort in the nose, nose pain, increased tear production, throat irritation, low urine output, rash, slow heart rate, increased liver enzymes, high blood pressure, and stuffy nose.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see accompanying Prescribing Information, including Boxed Warning and Medication Guide.